Due to the health consequences of handling cytotoxic agents, direct exposure to these drugs should be avoided, therefore protective measures should be used in compliance with protocols, so the use of cytotoxic safety cabinets is until now the first and most important measure to avoid and control exposure to cytostatic agents.
Toxic effects of cytotoxics affecting health
There is biological evidence of the absorption of the compounds of these drugs that affect the health of the nursing staff as laboratory technicians who prepare them, also it is necessary to take into account, certain parameters of the staff that influence the absorption of these compounds, however, the best way to avoid these effects is the use of safety cabinets for cytotoxics, some toxic effects are:
- Teratogenic.
- Cytostatic.
- Carcinogenic.
- Mutagenic.
- Corneal alteration.
- Cardiotoxic.
- Hepatotoxic.
- Nephrotoxic.
- Hemorrhagic.
- Vesicante.
- Irritating to skin and mucous membranes.
- Emetizing.
- Hematological.
When to use the cytotoxic safety cabinets
This type of biosafety cabinet type II is the only one that offers safety to work with cytotoxics, in addition they offer quality, reliability and ergonomics, and provide effective protection to the operator and the environment, in addition to a greater precaution of contamination of samples, in the case of cytotoxics that are dangerous particles, with agents that require Biosafety level 1, 2 or 3 containment.
They should be used in laboratories when they include working with antineoplastic drugs, genetic material, asbestos and other substances that generate dangerous airborne particles, the main function of these cabinets is to protect operators from the manipulated samples and at the same time, protect these samples from external contamination. Operator protection is provided by the creation of an air barrier formed by the entry of air from the room, through the front opening, and by the descending flow of sterile filtered air.
How the cytotoxic safety box works
Considering that they are designed to defogge strongly outward, their operation is as follows, the cabin air is drawn to the top of the cabin and reaches up to a HEPA filter, then this filtered air flows down through the work area. In this way the cabin air is also introduced into the inlet grille located in the working access opening. All contaminated air passes through the exhaust HEPA filter. With the exhaust system, 100% of the air is removed from the cabin and filtered out. Because air is recirculated, these biohazard cabinets can be used for work with agents treated with toxic chemicals and volatile radionuclides.
The KALSTEIN cytotoxic safety cabinet is the premium solution for cytotoxic/antineoplastic drug processing, providing the highest level of protection for the patient, pharmacist and environment. The unique demands of handling and preparing cytotoxic drugs for use in chemotherapy require a specialized cabinet, check it HERE
Characteristics of the safety cab for cytotoxic brand kalstein
- Remote control LCD display. All functions can be performed with it, making the large digital display easy to monitor all security.
- Operation much easier and more convenient. parameters at a glance and ergonomic size.
- The control panel improves the user interface.
- UV lamp for water and gas taps.
- High quality stainless steel. Emission of 253.7 nanometers for most.
- Efficient decontamination.
- Front window bag inlet and outlet bag filter.
- Motorized, two-layer laminated hardened PVC bag can ensure safety of glass > 5mm, anti UV. personal and the environment, and make the replacement process is convenient and fast.
If you want to purchase a cytotoxic safety box, please be aware to contact the best, this service we can offer you through our online channels and at the best price in the market, also if you want to know the catalog of high-end products that in KALSTEIN we have for you visit us https://kalstein.co.nz/ we assure you that through our online shopping channels that are very easy and viable from anywhere in the world, reminding them that we are Company manufacturer of Laboratory Equipment of high level sale. HERE